Anti-TGS1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA025024.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Catalyzes the 2 serial methylation steps for the conversion of the... more

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Product information "Anti-TGS1"

Protein function: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 93%

Keywords:	Anti-TGS1, Anti-PIMT, Anti-PIPMT, Anti-HCA137, EC=2.1.1.-, Anti-Trimethylguanosine synthase, Anti-CLL-associated antigen KW-2, Anti-Cap-specific guanine-N2 methyltransferase, Anti-Hepatocellular carcinoma-associated antigen 137
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA025024

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PELAKYWAQR YRLFSRFDDG IKLDREGWFS VTPEKIAEHI AGRVSQSFKC DVVVDAFCGV GGNTIQFALT GMRVIAIDID PVKIALARNN AE (ATA-APrEST76254)