Anti-TG, clone CL0164

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ATA-AMAb90523.25	25 µl		-		7 - 10 business days*		15 %	240.00€ 204.00€
ATA-AMAb90523.100	100 µl		-		7 - 10 business days*		15 %	358.00€ 304.30€

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Protein function: Acts as a substrate for the production of iodinated thyroid hormones thyroxine... more

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Product information "Anti-TG, clone CL0164"

Protein function: Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed:32025030, PubMed:17532758). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen (PubMed:32025030). Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (PubMed:32025030). One dimer produces 7 thyroid hormone molecules (PubMed:32025030). [The UniProt Consortium] Validated by standard strategies. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 76% and to rat: 76%. Epitope specificity: HDIERALVGKDLLGR.

Keywords:	Anti-Tg, Anti-Thyroglobulin
Supplier:	Atlas Antibodies
Supplier-Nr:	AMAb90523

Properties

Application:	IHC, WB
Antibody Type:	Monoclonal
Clone:	CL0164
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KMCSADYADL LQTFQVFILD ELTARGFCQI QVKTFGTLVS IPVCNNSSVQ VGCLTRERLG VNVTWKSRLE DIPVASLPDL HDIERALVGK DLLGRFTDLI QSGSFQLHLD SKTFPAETIR FLQGDHFGTS PRTWFGCSEG FYQVLTSEAS QDGLGCVKCP EGS (ATA-APrEST84470)