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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R30775 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Trefoil factor 1, also known as Estrogen... more
Product information "Anti-TFF1 antibody (Estrogen Inducible Protein)"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Trefoil factor 1, also known as Estrogen inducible factor pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that the protein in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of the protein in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. Protein function: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. [The UniProt Consortium]
Keywords: | Anti-Tff1, Anti-Bcei, Anti-Protein pS2, Anti-Trefoil factor 1, TFF1 antibody (Estrogen Inducible Protein) |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R30775 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | rat |
Immunogen: | Amino acid sequence from the middle region of mouse Estrogen Inducible Protein pS2 (CCFDDSVRGFPWCF) |
Format: | Purified |
Database Information
KEGG ID : | K22456 | Matching products |
UniProt ID : | Q08423 | Matching products |
Gene ID | GeneID 21784 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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