Anti-TDP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA071317.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA071317.100	100 µl		-		7 - 10 business days*		446.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: DNA repair enzyme that can remove a variety of covalent adducts from DNA... more

Close menu

Product information "Anti-TDP1"

Protein function: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead- end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 65% and to rat: 72%

Keywords:	Anti-TDP1, Anti-Tyr-DNA phosphodiesterase 1, Anti-Tyrosyl-DNA phosphodiesterase 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA071317

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: STSSLLCARQ GAANEPRYTC SEAQKAAHKR KISPVKFSNT DSVLPPKRQK SGSQEDLGWC LSSSDDELQP EM (ATA-APrEST90336)