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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay32271-100 | 100 µl | - |
6 - 10 business days* |
480.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Surfactant protein A (SP-A) is a hydrophilic surfactant protein and member of the collectin... more
Product information "Anti-Surfactant Protein A (C-Term) Rabbit Monoclonal Antibody (Clone RM334)"
Surfactant protein A (SP-A) is a hydrophilic surfactant protein and member of the collectin family with roles in microbial and apoptotic cell phagocytosis, as well as the regulation of cytokine expression. It is composed of an N-terminal cysteine-rich domain that facilitates crosslinking of SP-A monomers, a collagen-like domain that induces multimerization, and a C-terminal carbohydrate recognition domain (CRD) for pathogen recognition. SP-A is expressed primarily in pulmonary surfactant but is also expressed in the brain, kidney, and female reproductive tract. It functions as an octadecamer that binds bacterial, fungal, and viral pathogens to enhance opsonized phagocytosis. SP-A interacts with toll-like receptors to modulate the production of various cytokines and inflammatory mediators in response to infection. Serum levels of SP-A are associated with early relapse or exacerbation in patients with chronic obstructive pulmonary disease (COPD). Cayman's Surfactant Protein A (C-Term) Rabbit Monoclonal Antibody (Clone RM334) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.Synonyms: SP-A. Immunogen: Peptide from the C-terminal region of human surfactant protein A. Clone Designation: RM334. Formulation: (Request formulation change), 100 µl of protein A-affinity purified monoclonal antibody. Storage Buffer: PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide. Host: Rabbit. Isotype: IgG. Applications: IHC, WB. Cross Reactivity: (+) Surfactant protein A.
Keywords: | SP-A |
Supplier: | Cayman Chemical |
Supplier-Nr: | 32271 |
Properties
Application: | IHC, WB |
Antibody Type: | Monoclonal |
Clone: | RM334 |
Conjugate: | No |
Host: | Rabbit |
Immunogen: | Peptide from the C-terminal region of human surfactant protein A |
Format: | Purified |
Database Information
KEGG ID : | K10067 | Matching products |
UniProt ID : | Q8IWL1 | Matching products |
Gene ID | GeneID 729238 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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