Anti-STRADB

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-14553.20 20 µl - -

7 - 16 business days*

80.00€
E-AB-14553.60 60 µl - -

7 - 16 business days*

156.00€
E-AB-14553.120 120 µl - -

7 - 16 business days*

262.00€
E-AB-14553.200 200 µl - -

7 - 16 business days*

459.00€
 
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily.... more
Product information "Anti-STRADB"
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Protein function: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. [The UniProt Consortium]
Keywords: Anti-STRADB, Anti-CALS-21, Anti-ALS2CR2, Anti-PRO1038, Anti-STRAD beta, Anti-Pseudokinase ALS2CR2, Anti-ILP-interacting protein, Anti-STE20-related kinase adapter protein beta, STRADB Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-14553

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Recombinant protein of human STRADB
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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