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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
REV-31-1365-00-R100 | 100 µl | - | - |
3 - 9 business days* |
483.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
STAT6 (Signal transducer and activator of transcription 6) is a transcription factor that belongs... more
Product information "Anti-Stat6, Rabbit Monoclonal (RM473)"
STAT6 (Signal transducer and activator of transcription 6) is a transcription factor that belongs to the Signal Transducer and Activator of Transcription (STAT) family of proteins. The proteins of STAT family transmit signals from a receptor complex to the nucleus and activate gene expression. STAT6 is activated by the binding of interleukin-4 (IL-4) to its receptor. IL-4 is a cytokine that is produced by T cells, B cells, and mast cells. When IL-4 binds to its receptor, it triggers a series of events that lead to the phosphorylation of STAT6. Phosphorylated STAT6 then dimerizes and translocates to the nucleus, where it binds to DNA and activates the transcription of a number of genes. The genes that are activated by STAT6 play a role in a number of different biological processes, including Th2 cell differentiation, IgE production, eosinophil differentiation, mast cell activation and is involved in the development of some types of cancer.
Keywords: | Anti-STAT6, Anti-IL-4 Stat, Anti-Signal transducer and activator of transcription 6 |
Supplier: | RevMAb Biosciences |
Supplier-Nr: | 31-1365-00 |
Properties
Application: | IHC, WB |
Antibody Type: | Monoclonal |
Clone: | RM473 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A peptide corresponding to residues near the C-terminus of human Stat6. |
Format: | Liquid |
Database Information
KEGG ID : | K11225 | Matching products |
UniProt ID : | P42226 | Matching products |
Gene ID | GeneID 6778 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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