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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG58234.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin... more
Product information "Anti-STAMBP / AMSH"
Protein function: Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways. [The UniProt Consortium]
| Keywords: | Anti-AMSH, Anti-STAMBP, EC=3.4.19.-, Anti-STAM-binding protein, Anti-Endosome-associated ubiquitin isopeptidase, Anti-Associated molecule with the SH3 domain of STAM |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG58234 |
Properties
| Application: | ICC, IF, IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant funsion protein corresponding to aa. 100-270 of Human STAMBP (NP_998787.1) |
| MW: | 48 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K11866 | Matching products |
| UniProt ID : | O95630 | Matching products |
| Gene ID | GeneID 10617 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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