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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V8095SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. Spectrin, an actin binding protein that is a... more
Product information "Anti-SPTAN1 / Alpha II Spectrin / Fodrin / NEAS, clone SPTAN1/3351"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin II (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein. Protein function: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. [The UniProt Consortium]
Keywords: | Anti-NEAS, Anti-SPTAN1, Anti-Alpha-II spectrin, Anti-Fodrin alpha chain, Anti-Spectrin, non-erythroid alpha subunit, Anti-Spectrin alpha chain, non-erythrocytic 1, SPTAN1 Antibody / Alpha II Spectrin / Fodrin / NEAS |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V8095SAF |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | SPTAN1/3351 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A recombinant human partial protein (amino acids 2351-2475) |
Format: | Purified |
Database Information
KEGG ID : | K06114 | Matching products |
UniProt ID : | Q13813 | Matching products |
Gene ID | GeneID 6709 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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