Anti-SPSB1

Anti-SPSB1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG40067.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box... more
Product information "Anti-SPSB1"
Protein function: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:15601820, PubMed:21199876). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:21199876). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed:21199876). [The UniProt Consortium]
Keywords: Anti-SSB1, Anti-SSB-1, Anti-SPSB1, Anti-SPRY domain-containing SOCS box protein 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG40067

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant fusion protein corresponding to aa. 1-60 of Human SPSB1 (NP_079382.2)
MW: 30 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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