Anti-Splicing regulator SDE2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ7495 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Splicing regulator SDE2 enables damaged... more
Product information "Anti-Splicing regulator SDE2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Splicing regulator SDE2 enables damaged DNA binding activity. Involved in several processes, including cellular response to UV, mitotic G1 DNA damage checkpoint signaling, and protein ubiquitination. Located in several cellular components, including Golgi apparatus, cytosol, and nuclear speck. Protein function: Inhibits translesion DNA synthesis by preventing monoubiquitination of PCNA, this is necessary to counteract damage due to ultraviolet light-induced replication stress (PubMed:27906959). SDE2 is cleaved following PCNA binding, and its complete degradation is necessary to allow S-phase progression following DNA damage (PubMed:27906959). [The UniProt Consortium]
Keywords: Anti-SDE2, Anti-C1orf55, Anti-Splicing regulator SDE2, Anti-Replication stress response regulator SDE2, Splicing regulator SDE2 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: RQ7495

Properties

Application: WB, IF, FC, IHC (paraffin), Direct ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: E. coli-derived recombinant human protein (amino acids I10-K447)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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