Anti-Splicing factor SF3B4(Clone: 3A1)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-34-1113-100	100 µl		-		3 - 11 business days*		789.00€

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Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B... more

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Product information "Anti-Splicing factor SF3B4(Clone: 3A1)"

Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077). [The UniProt Consortium]

Keywords:	Anti-SF3B4, Anti-SAP49, Anti-SAP 49, Anti-Splicing factor 3B subunit 4, Anti-Spliceosome-associated protein 49, Anti-Pre-mRNA-splicing factor SF3b 49 kDa subunit, Monoclonal Antibody to Splicing factor SF3B4(Clone: 3A1)
Supplier:	Abeomics
Supplier-Nr:	34-1113

Properties

Application:	WB, IF/ICC, IHC
Antibody Type:	Monoclonal
Clone:	3A1
Conjugate:	No
Host:	Mouse
Species reactivity:	human, bovine, pig, mouse, rat
Immunogen:	Full length recombinant human SF3B4 expressed in and purified from E. coli
Format:	Purified