Anti-SPIRE1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA040737.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA040737.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Acts as an actin nucleation factor, remains associated with the slow-growing... more

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Product information "Anti-SPIRE1"

Protein function: Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:11747823, PubMed:21620703). Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (PubMed:11747823). Required for asymmetric spindle positioning and asymmetric cell division during meiosis (PubMed:21620703). Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (PubMed:21620703). Also acts in the nucleus: together with FMN2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (PubMed:26287480). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 83%

Keywords:	Anti-Spir-1, Anti-KIAA1135, Anti-Protein spire homolog 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA040737

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LEEIKAERKL RPVSPEEIRR SRLDVTTPES TKNLVESSMV NGGLTSQTKE NGLSTSQQVP AQRKKLLRAP TLAELDSSES EEETLHK (ATA-APrEST81727)