Anti-SOX2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-35-1679-50	50 µl		-		3 - 11 business days*		574.00€

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Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression... more

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Product information "Anti-SOX2"

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency Protein function: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Binds to the proximal enhancer region of NANOG. Critical for early embryogenesis and for embryonic stem cell pluripotency (PubMed:18035408). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. May function as a switch in neuronal development. [The UniProt Consortium]

Keywords:	Anti-SOX2, Anti-Transcription factor SOX-2, Polyclonal Antibody to SOX2
Supplier:	Abeomics
Supplier-Nr:	35-1679-50

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide sequence around aa.76~80 (G-A-E-W-K) derived from SOX2
Format:	Purified