Anti-SOSB1

Anti-SOSB1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES19030.50 50 µl - -

Request delivery time estimate

169.00€
ELK-ES19030.100 100 µl - -

Request delivery time estimate

283.00€
 
Protein function: Component of the SOSS complex, a multiprotein complex that functions downstream... more
Product information "Anti-SOSB1"
Protein function: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint (PubMed:25249620). In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM- dependent signaling pathways. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Nucleus . Localizes to nuclear foci following DNA damage. Foci formation is not cell-cycle dependent. Partial colocalization with RAD51 after ionizing radiation treatment.
Keywords: Anti-NABP2, Anti-hSSB1, Anti-LP3587, Anti-OBFC2B, Anti-SOSS-B1, Anti-SOSS complex subunit B1, Anti-Sensor of ssDNA subunit B1, Anti-Nucleic acid-binding protein 2, Anti-Single-stranded DNA-binding protein 1, SOSB1 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES19030

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthesized peptide derived from human SOSB1 AA range: 70-120
Format: Purified

Database Information

UniProt ID : Q9BQ15 | Matching products
Gene ID GeneID 79035 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-SOSB1"
Write a review
or to review a product.
Viewed