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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG63224.100 | 100 µg | - | - |
6 - 14 business days* |
784.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: SOCS family proteins form part of a classical negative feedback system that... more
Product information "Anti-SOCS3, C-terminal"
Protein function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL-6 signaling in vivo. Probable substrate recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize IL6ST. [The UniProt Consortium]
Keywords: | Anti-CIS3, Anti-CIS-3, Anti-SSI-3, Anti-SOCS3, Anti-SOCS-3, Anti-STAT-induced STAT inhibitor 3, Anti-Cytokine-inducible SH2 protein 3, Anti-Suppressor of cytokine signaling 3 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG63224 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human (Expected: mouse, rat, canine, swine, bovine) |
Immunogen: | C-PIREFLDQYDAPL |
Format: | Ammonium Sulfate Precipitated |
Database Information
KEGG ID : | K04696 | Matching products |
UniProt ID : | O14543 | Matching products |
Gene ID | GeneID 9021 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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