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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F51354-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F51354-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. SOCS1 is a member of the STAT-induced STAT inhibitor... more
Product information "Anti-SOCS1"
In 1X PBS, pH 7.4, with 0.09% sodium azide. SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling(SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. Protein function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein- tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron survival. Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize JAK2. SOCS1 appears to be a negative regulator in IGF1R signaling pathway. [The UniProt Consortium]
Keywords: | Anti-JAB, Anti-SSI1, Anti-SOCS1, Anti-TIP-3, Anti-SSI-1, Anti-SOCS-1, Anti-JAK-binding protein, Anti-Tec-interacting protein 3, Anti-STAT-induced STAT inhibitor 1, Anti-Suppressor of cytokine signaling 1, SOCS1 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F51354 |
Properties
Application: | WB, IHC, IF, FC, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | A portion of amino acids 35-66 from the human protein was used as the immunogen for this SOCS1 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K04694 | Matching products |
UniProt ID : | O15524 | Matching products |
Gene ID | GeneID 8651 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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