Anti-SnoN

Anti-SnoN
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES3473.50 50 µl - -

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169.00€
ELK-ES3473.100 100 µl - -

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283.00€
 
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth... more
Product information "Anti-SnoN"
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011], Protein function: May have regulatory role in cell division or differentiation in response to extracellular signals. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: acrosomal vesicle,nucleus,nucleoplasm,transcription factor complex,cytoplasm,PML body,transcriptional repressor complex,protein complex,
Keywords: Anti-SNO, Anti-SKIL, Anti-Ski-like protein, Anti-Ski-related protein, Anti-Ski-related oncogene, SnoN rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES3473

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: The antiserum was produced against synthesized peptide derived from human SKIL. AA range:616-665
MW: 77 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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