Anti-SNAIL

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R35656-100UG	100 µg		-	-	3 - 10 business days*		755.00€

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0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more

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Product information "Anti-SNAIL"

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: SNAI1, SLUGH2, SNA, SNAH Protein function: Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up- regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself. [The UniProt Consortium]

Keywords:	Anti-SNAH, Anti-SNAI1, Anti-Protein sna, Anti-Protein snail homolog 1, Anti-Zinc finger protein SNAI1, SNAIL Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R35656

Properties

Application:	WB, IHC, ELISA (peptide), IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human, mouse
Immunogen:	Amino acids RKPSDPNRKPNY were used as the immunogen for this SNAIL antibody.
Format:	Purified