Anti-SMYD2

Anti-SMYD2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES3470.50 50 µl - -

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169.00€
ELK-ES3470.100 100 µl - -

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283.00€
 
SET and MYND domain containing 2(SMYD2) Homo sapiens SET domain-containing proteins, such as... more
Product information "Anti-SMYD2"
SET and MYND domain containing 2(SMYD2) Homo sapiens SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008], Protein function: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000. Cellular localization: Cytoplasm, cytosol . Nucleus .
Keywords: Anti-KMT3C, Anti-SMYD2, Anti-HSKM-B, Anti-Lysine N-methyltransferase 3C, Anti-Histone methyltransferase SMYD2, Anti-N-lysine methyltransferase SMYD2, Anti-SET and MYND domain-containing protein 2, SMYD2 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES3470

Properties

Application: WB, ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: The antiserum was produced against synthesized peptide derived from human SMYD2. AA range:99-148
MW: 50 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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