Anti-SMG8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA024841.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA024841.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop... more

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Product information "Anti-SMG8"

Protein function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 97%

Keywords:	Anti-ABC2, Anti-SMG8, Anti-Protein SMG8, Anti-Protein smg-8 homolog, Anti-Amplified in breast cancer gene 2 protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA024841

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SINCLFTVPA NQAFVYIVPG SQEEDPVGML LDQLRSHCTV KDPESLLVPA PLSGPRRYQV MRQHSRQQLS FHIDSSSSSS SGQLVDFTLR EFLWQHVELV LSKKGFDDSV GRNPQPSHFE LPTYQKWISA ASK (ATA-APrEST75755)