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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
S1014-52Y.50 | 50 µg | - | - |
3 - 19 business days* |
901.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SMAD3 is a 50kD transcriptional modulator activated by TGF-beta and activin type 1 receptor... more
Product information "Anti-SMAD3 (Mothers Against Decapentaplegic Homolog 3, Mothers Against DPP Homolog 3, MAD Homolog 3,"
SMAD3 is a 50kD transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD3 functions in cell proliferation, differentiation and development. Upon stimulation, SMAD3 oligomerizes with SMAD4 and translocates into the nucleus where it binds to DNA and transcription factors. SMAD3 activity induces differentiation of selected neuronal subtypes at the expense of other subtypes. Studies have indicated that defects in SMAD3 may be a cause of colorectal cancer. , Applications:, Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 2.5ug/ml, ELISA: 1:25,000-1:100,000, Western Blot: 1:2,000-1:20,000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-hMAD-3, Anti-hSMAD3, Anti-MAD homolog 3, Anti-SMAD family member 3, Anti-Mothers against DPP homolog 3, Anti-Mothers against decapentaplegic homolog 3 |
Supplier: | United States Biological |
Supplier-Nr: | S1014-52Y |
Properties
Application: | ELISA, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | bovine, chicken, human, mouse, swine, rat, zebrafish |
Immunogen: | Synthetic peptide corresponding to aa417-425 of human SMAD3. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K23605 | Matching products |
UniProt ID : | P84022 | Matching products |
Gene ID | GeneID 4088 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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