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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1283-0.1 | 100 µg | - |
3 - 11 business days* |
654.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SLP76 (SH2 domain-containing leukocyte protein of 76 kDa) is a cytosolic adaptor protein which... more
Product information "Anti-SLP76 Polyclonal Antibody"
SLP76 (SH2 domain-containing leukocyte protein of 76 kDa) is a cytosolic adaptor protein which translocates to the plasma mambrane and is involved in multiple signaling pathways in T cells, mast cells, neutrophils and platelets, B cells express its analog SLP65/BLNK (B cell linker protein). SLP76 is phosphorylated by Syk-family and Tec-family tyrosine kinases and couples them to the phosphorylation and activation of PLC-gamma. Via Gads or Grb2, SLP76 also associates with LAT adaptor by involvement of SLP76 proline-rich region. The SH2 domain of SLP76 has been identified as the region involved in binding the serine/threonine kinase HPK1. HPK1 may act as both a positive and a negative regulator by promoting the Jnk-mitogen activated protein kinase (MAPK) pathway and inhibiting the pathway leading to AP-1 activation. Protein function: Involved in T-cell antigen receptor mediated signaling. [The UniProt Consortium]
Keywords: | Anti-LCP2, Anti-SLP76, Anti-SLP-76 tyrosine phosphoprotein, Anti-Lymphocyte cytosolic protein 2, Anti-SH2 domain-containing leukocyte protein of 76 kDa, Anti-SLP76 Polyclonal Antibody |
Supplier: | Abeomics |
Supplier-Nr: | 30-1283 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Bacterially expressed fusion protein representing amino acids 216-434 of human SLP76 with histidine tag |
Format: | Purified |
Database Information
KEGG ID : | K07361 | Matching products |
UniProt ID : | Q13094 | Matching products |
Gene ID | GeneID 3937 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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