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Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A302-436A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A302-436A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3... more
Product information "Anti-SKP2"
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, thereby regulating cell migration. [The UniProt Consortium]
Keywords: | Anti-SKP2, Anti-FBXL1, Anti-p45skp2, Anti-F-box protein Skp2, Anti-F-box/LRR-repeat protein 1, Anti-S-phase kinase-associated protein 2, Anti-Cyclin-A/CDK2-associated protein p45 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-436A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A302-436A-T maps to a region between residue 1 and 50 of human S-phase kinase-associated protein 2 using the numbering given in entry NP_005974.2 (GeneID 6502). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K03875 | Matching products |
UniProt ID : | Q13309 | Matching products |
Gene ID | GeneID 6502 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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