Anti-SIN3A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA047213.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA047213.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1... more

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Product information "Anti-SIN3A"

Protein function: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. Required for cortical neuron differentiation and callosal axon elongation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%

Keywords:	Anti-Transcriptional corepressor Sin3a, Anti-Paired amphipathic helix protein Sin3a, Anti-Histone deacetylase complex subunit Sin3a
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA047213

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SDDPVEAERW SDYVERYMNS DTTSPELREH LAQKPVFLPR NLRRIRKCQR GREQQEKEGK EGNSKKTMEN VDSLDKLECR FKLNSYKMVY VIKSEDYMYR RTALLRAHQS HERVSK (ATA-APrEST87485)