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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA045191.25 | 25 µl | - |
7 - 10 business days* |
300.00€
|
|||
ATA-HPA045191.100 | 100 µl | - |
7 - 10 business days* |
421.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Major sphingomyelin synthase at the Golgi apparatus (PubMed:17449912,... more
Product information "Anti-SGMS1"
Protein function: Major sphingomyelin synthase at the Golgi apparatus (PubMed:17449912, PubMed:14685263). Catalyzes the reversible transfer of phosphocholine moiety in sphingomyelin biosynthesis: in the forward reaction transfers phosphocholine head group of phosphatidylcholine (PC) on to ceramide (CER) to form ceramide phosphocholine (sphingomyelin, SM) and diacylglycerol (DAG) as by-product, and in the reverse reaction transfers phosphocholine from SM to DAG to form PC and CER. The direction of the reaction depends on the levels of CER and DAG in Golgi membranes (PubMed:14685263, PubMed:17449912, PubMed:14976195, PubMed:17982138, PubMed:19454763). Does not use free phosphorylcholine or CDP-choline as donor (PubMed:14976195, PubMed:14685263). Regulates receptor-mediated signal transduction via mitogenic DAG and proapoptotic CER, as well as via SM, a structural component of membrane rafts that serve as platforms for signal transduction and protein sorting (PubMed:14976195, PubMed:17449912, PubMed:17982138). Plays a role in secretory transport via regulation of DAG pool at the Golgi apparatus and its downstream effects on PRKD1 (PubMed:18370930, PubMed:21980337). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 95%
Keywords: | Anti-MOB, Anti-SGMS1, Anti-Protein Mob, Anti-Sphingomyelin synthase 1, Anti-Transmembrane protein 23, Anti-Medulla oblongata-derived protein, Anti-Phosphatidylcholine:ceramide cholinephosphotransferase 1 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA045191 |
Properties
Application: | WB, IHC, ICC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ASTMKEVVYW SPKKVADWLL ENAMPEYCEP LEHFTGQDLI NLTQEDFKKP PLCRVSSDNG QRLLDMIETL KMEHHLEAHK NGHANGHLNI GVDIPTPDGS FSIKIKPNGM PNGYRKEMIK IPM (ATA-APrEST73324) |
Database Information
KEGG ID : | K04714 | Matching products |
UniProt ID : | Q86VZ5 | Matching products |
Gene ID | GeneID 259230 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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