Anti-SF3B6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA034830.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA034830.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B... more

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Product information "Anti-SF3B6"

Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (PubMed:12234937). Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing (PubMed:16432215). Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively (PubMed:16432215). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 95%

Keywords:	Anti-SF3B6, Anti-SAP14, Anti-SF3B14a, Anti-CGI-110, Anti-SF3b 14 kDa subunit, Anti-Splicing factor 3B subunit 6, Anti-Pre-mRNA branch site protein p14, Anti-Splicing factor 3b, subunit 6, 14kDa, Anti-Spliceosome-associated protein, 14-kDa
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA034830

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MAMQAAKRAN IRLPPEVNRI LYIRNLPYKI TAEEMYDIFG KYGPIRQIRV GNTPETRGTA YVV (ATA-APrEST78962)