Anti-SCUBE2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA029871.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA029871.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Lipid-binding protein required for SHH long-range signaling by binding to the... more

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Product information "Anti-SCUBE2"

Protein function: Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane (PubMed:22902404, PubMed:22677548). Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface (PubMed:24522195). Synergizes with DISP1 to increase SHH secretion (PubMed:22902404). Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis (PubMed:27834687). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 83%

Keywords:	Anti-CEGP1, Anti-Scube/You, Anti-Protein CEGP1, Anti-Signal peptide, CUB and EGF-like domain-containing protein 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA029871

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SGIHLSSDVT TIRTSVTFKL NEGKCSLKNA ELFPEGLRPA LPEKHSSVKE SFRYVNLTCS SGKQVPGAPG RPSTPKEMFI TVEFELETNQ KEVTASCDLS CIVKRTEKRL RKAIRTLRKA VHREQFHLQL SGMNLDVAK (ATA-APrEST70279)