Anti-SASH1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES13196.50	50 µl		-	-	Request delivery time estimate		169.00€
ELK-ES13196.100	100 µl		-	-	Request delivery time estimate		283.00€

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Protein function: Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation.... more

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Product information "Anti-SASH1"

Protein function: Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation (PubMed:23776175). Regulates TRAF6 and MAP3K7 ubiquitination (PubMed:23776175). Involved in the regulation of cell mobility (PubMed:23333244, PubMed:23776175, PubMed:25315659). Regulates lipolysaccharide (LPS)-induced endothelial cell migration (PubMed:23776175). Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis (PubMed:23333244). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300. Cellular localization: Cytoplasm .

Keywords:	Anti-SASH1, Anti-KIAA0790, Anti-SAM and SH3 domain-containing protein 1, Anti-Proline-glutamate repeat-containing protein, SASH1 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES13196

Properties

Application:	WB, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from human SASH1 AA range: 373-423
Format:	Purified

Database Information

KEGG ID :	K23705 \| Matching products
UniProt ID :	O94885 \| Matching products
Gene ID	GeneID 23328 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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