Anti-SARS-CoV-2 Spike Protein S1 (Rec, blocking) (Clone: Covi-2) (Azide free)

COVID-19 Research

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-29-1010	100 µg		-		3 - 11 business days*		648.00€

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Protein function: [Spike protein S1]: attaches the virion to the cell membrane by interacting... more

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Product information "Anti-SARS-CoV-2 Spike Protein S1 (Rec, blocking) (Clone: Covi-2) (Azide free)"

Protein function: [Spike protein S1]: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes. [The UniProt Consortium]

Keywords:	Anti-Spike glycoprotein, Anti-S glycoprotein
Supplier:	Abeomics
Supplier-Nr:	29-1010

Properties

Application:	FA (blocking), ELISA, WB
Antibody Type:	Monoclonal
Clone:	Covi-2
Conjugate:	No
Host:	Human
Species reactivity:	SARS-CoV-2
Immunogen:	Recombinant SARS-CoV-2 Spike Protein S1 receptor binding domain
Format:	Purified