Anti-SARS

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA016939.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine... more

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Product information "Anti-SARS"

Protein function: Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:9431993, PubMed:26433229, PubMed:28236339). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (PubMed:9431993, PubMed:26433229, PubMed:28236339). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC (PubMed:24940000). Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA (PubMed:19423848, PubMed:19423847, PubMed:24940000). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 93%

Keywords:	Anti-SARS, Anti-SerRS, Anti-Seryl-tRNA synthetase, Anti-Seryl-tRNA(Ser/Sec) synthetase, Anti-Serine--tRNA ligase, cytoplasmic
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA016939

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: NVLSFDDLTA DALANLKVSQ IKKVRLLIDE AILKCDAERI KLEAERFENL REIGNLLHPS VPISNDEDVD NKVERIWGDC TVRKKYSHVD LVVMVDGFEG EKGAVVAGSR GYFLKGVLVF LEQALIQYAL (ATA-APrEST70299)