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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES13217.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES13217.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and... more
Product information "Anti-SAC2"
The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011], Protein function: Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869669). Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed:25869669). Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895). Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed:25476455). Functionally important modulator of cardiac myocyte size and of the cardiac response to stress. May play a role as negative regulator of axon regeneration after central nervous system injuries. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Membrane, clathrin-coated pit . Early endosome . Recycling endosome . Also found on macropinosomes. .
Keywords: | Anti-hSAC2, Anti-MSTP007, Anti-KIAA0966, Anti-Inositol polyphosphate 5-phosphatase F, Anti-Phosphatidylinositide phosphatase SAC2, Anti-Sac domain-containing inositol phosphatase 2, Anti-Sac domain-containing phosphoinositide 4-phosphatase 2, SAC2 rabbit |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES13217 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from human SAC2 AA range: 1006-1056 |
Format: | Purified |
Database Information
KEGG ID : | K21798 | Matching products |
UniProt ID : | Q9Y2H2 | Matching products |
Gene ID | GeneID 22876 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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