Anti-S100A11, clone S100A11/7393

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. S100A11 is a Ca2+-binding protein of the S100 family. The proteins comprising the S-100 protein family have two EF-hand structures per molecule of protein. Expression of these family members occurs primarily in neurons or retinal photoreceptor cells, and may also be involved in a wide variety of cellular functions including cell growth, cell-cell communication, energy metabolism and intracellular signal transduction. They have also been linked to various pathologies, including Alzheimer s disease, schizophrenia and cancer. S100A11 is highly expressed in lung tissue and is also expressed in kidney, liver, brain, heart and smooth muscle. It is an important androgen-responsive protein produced by Sertoli cells and might play a role in spermatogenesis regulation. Protein function: Facilitates the differentiation and the cornification of keratinocytes. [The UniProt Consortium]