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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA038487.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
| ATA-HPA038487.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Essential component of the eNoSC (energy-dependent nucleolar silencing)... more
Product information "Anti-RRP8"
Protein function: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 93% and to rat: 92%
| Keywords: | Anti-RRP8, Anti-hucep-1, Anti-KIAA0409, EC=2.1.1.-, Anti-Nucleomethylin, Anti-Cerebral protein 1, Anti-Ribosomal RNA-processing protein 8 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA038487 |
Properties
| Application: | ICC, IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AQRLFQEDPE AFLLYHRGFQ SQVKKWPLQP VDRIARDLRQ RPASLVVADF GCGDCRLASS IRNSVHCFDL ASLDPRVTVC DMAQVPLEDE SVDVAVFC (ATA-APrEST80563) |
Database Information
| KEGG ID : | K14850 | Matching products |
| UniProt ID : | O43159 | Matching products |
| Gene ID | GeneID 23378 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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