Anti-RRAGC

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA055489.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA055489.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Guanine nucleotide-binding protein that plays a crucial role in the cellular... more

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Product information "Anti-RRAGC"

Protein function: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade (PubMed:20381137, PubMed:27234373, PubMed:24095279). Forms heterodimeric Rag complexes with RRAGA or RRAGB and cycles between an inactive GTP-bound and an active GDP-bound form (PubMed:24095279). In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB (PubMed:20381137, PubMed:27234373, PubMed:24095279). This is a crucial step in the activation of the TOR signaling cascade by amino acids (PubMed:20381137, PubMed:27234373, PubMed:24095279). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-RagC, Anti-Rag C, Anti-TIB929, Anti-GTPase-interacting protein 2, Anti-Ras-related GTP-binding protein C
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA055489

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MSLQYGAEET PLAGSYGAAD SFPKDFGYGV EEEEEE (ATA-APrEST91655)