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Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. [provided by RefSeq, Mar 2017] Protein function: May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (PubMed:12077123). Plays a role in the recruitment of PRDX3 to early endosomes (PubMed:15750338). [The UniProt Consortium]
Keywords:
RPK118, RPS6KC1, S6K-delta-1, EC=2.7.11.1, SPHK1-binding protein, 52 kDa ribosomal protein S6 kinase, Ribosomal protein S6 kinase delta-1, Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein, RPS6KC1 Polyclonal Antibody
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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