Anti-RNF5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-594A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-594A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together... more

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Product information "Anti-RNF5"

Protein function: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses. [The UniProt Consortium]

Keywords:	Anti-G16, Anti-RNF5, Anti-HsRma1, EC=2.3.2.27, Anti-Protein G16, Anti-Ram1 homolog, Anti-RING finger protein 5, Anti-E3 ubiquitin-protein ligase RNF5, Anti-RING-type E3 ubiquitin transferase RNF5
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-594A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat)
Immunogen:	synthetic peptide. The epitope recognized by A303-594A-T maps to a region between residue 1 and 50 of human Ring Finger Protein 5 using the numbering given in entry NP_008844.1 (GeneID 6048).
Format:	Antigen Affinity Purified