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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F43770-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F43770-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene contains a RING... more
Product information "Anti-RNF40"
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Protein function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. [The UniProt Consortium]
Keywords: | Anti-RNF40, Anti-RBP95, Anti-BRE1B, Anti-BRE1-B, EC=6.3.2.-, Anti-RING finger protein 40, Anti-E3 ubiquitin-protein ligase BRE1B, Anti-95 kDa retinoblastoma-associated protein, RNF40 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F43770 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 697-725 from the human protein was used as the immunogen for this RNF40 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K10696 | Matching products |
UniProt ID : | O75150 | Matching products |
Gene ID | GeneID 9810 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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