Anti-RNF113A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA076658.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA076658.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Required for pre-mRNA splicing as component of the spliceosome... more

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Product information "Anti-RNF113A"

Protein function: Required for pre-mRNA splicing as component of the spliceosome (PubMed:29361316, PubMed:29360106). E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins (PubMed:28978524, PubMed:29144457). Catalyzes polyubiquitination of SNRNP200/BRR2 with non-canonical 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Plays a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit ALKBH3 and the ASCC complex to sites of DNA damage by alkylating agents (PubMed:29144457). Ubiquitinates CXCR4, leading to its degradation, and thereby contributes to the termination of CXCR4 signaling (PubMed:28978524). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 63% and to rat: 66%

Keywords:	Anti-RNF113, Anti-RNF113A, Anti-Cwc24 homolog, Anti-Zinc finger protein 183, Anti-RING finger protein 113A, Anti-E3 ubiquitin-protein ligase RNF113A
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA076658

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PAKELIAKLE KHRATGEGGA SDLPEDPDED AIPIT (ATA-APrEST94449)