Anti-RN157

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES13373.50	50 µl		-	-	Request delivery time estimate		169.00€
ELK-ES13373.100	100 µl		-	-	Request delivery time estimate		283.00€

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Protein function: E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the... more

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Product information "Anti-RN157"

Protein function: E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons (PubMed:25342469). Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical (PubMed:25342469). May act as a scaffold molecule to regulate this process (PubMed:25342469). Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle (PubMed:28655764). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000. Cellular localization: Cytoplasm .

Keywords:	Anti-RNF157, Anti-KIAA1917, Anti-RING finger protein 157, Anti-E3 ubiquitin ligase RNF157, Anti-RING-type E3 ubiquitin transferase RNF157, RN157 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES13373

Properties

Application:	WB, ELISA, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from human RN157 AA range: 588-638
Format:	Purified

Database Information

KEGG ID :	K25192 \| Matching products
UniProt ID :	Q96PX1 \| Matching products
Gene ID	GeneID 114804 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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