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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-CAB20171.50 | 50 µl | - |
9 - 20 business days* |
352.00€
|
|||
| G-CAB20171.100 | 100 µl | - |
9 - 20 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Constitutes one of the E3 ubiquitin-protein ligases that mediate... more
Product information "Anti-RING1A"
Protein function: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity. [The UniProt Consortium]
| Keywords: | Anti-RNF1, Anti-RING1, EC=2.3.2.27, Anti-RING finger protein 1, Anti-Polycomb complex protein RING1, Anti-E3 ubiquitin-protein ligase RING1, Anti-Really interesting new gene 1 protein, Anti-RING-type E3 ubiquitin transferase RING1, RING1A Rabbit pAb |
| Supplier: | Assay Genie |
| Supplier-Nr: | CAB20171 |
Properties
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant protein of human RING1A A. |
Database Information
| KEGG ID : | K10695 | Matching products |
| UniProt ID : | Q06587 | Matching products |
| Gene ID | GeneID 6015 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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