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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-CAB13604.50 | 50 µl | - | - |
9 - 20 business days* |
352.00€
|
||
G-CAB13604.100 | 100 µl | - |
9 - 20 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
IF 1:50 - 1:200. Protein function: E3 ubiquitin-protein ligase that regulates several biological... more
Product information "Anti-RFFL"
IF 1:50 - 1:200. Protein function: E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Mediates 'Lys-48'-linked polyubiquitination of PRR5L and its subsequent proteasomal degradation thereby indirectly regulating cell migration through the mTORC2 complex. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. Negatively regulates the tumor necrosis factor-mediated signaling pathway through targeting of RIPK1 to ubiquitin-mediated proteasomal degradation. Negatively regulates p53/TP53 through its direct ubiquitination and targeting to proteasomal degradation. Indirectly, may also negatively regulate p53/TP53 through ubiquitination and degradation of SFN. May also play a role in endocytic recycling. [The UniProt Consortium]
Keywords: | Anti-Fring, Anti-RNF189, Anti-CARP-2, Anti-Caspase regulator CARP2, Anti-RING finger protein 189, Anti-RING finger protein 34-like, Anti-FYVE-RING finger protein Sakura, Anti-E3 ubiquitin-protein ligase rififylin, RFFL Polyclonal Antibody (CAB13604) |
Supplier: | Assay Genie |
Supplier-Nr: | CAB13604 |
Properties
Application: | IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Database Information
KEGG ID : | K20804 | Matching products |
UniProt ID : | Q8WZ73 | Matching products |
Gene ID | GeneID 117584 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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