Anti-RBL2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA019703.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA019703.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Key regulator of entry into cell division. Directly involved in heterochromatin... more

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Product information "Anti-RBL2"

Protein function: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 91%

Keywords:	Anti-RB2, Anti-RBL2, Anti-p130, Anti-pRb2, Anti-RBR-2, Anti-Retinoblastoma-like protein 2, Anti-Retinoblastoma-related protein 2, Anti-130 kDa retinoblastoma-associated protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA019703

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IAGSPLTPRR VTEVRADTGG LGRSITSPTT LYDRYSSPPA STTRRRLFVE NDSPSDGGTP GRMPPQPLVN AVPVQNVSGE TVSVTPVPGQ TLVTMATATV TANNGQTVTI PVQGIANENG GITFFPVQV (ATA-APrEST73689)