Anti-RBL1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
G-CAB20518.50	50 µl		-		9 - 20 business days*		352.00€
G-CAB20518.100	100 µl		-		9 - 20 business days*		448.00€

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Protein function: Key regulator of entry into cell division (PubMed:17671431). Directly involved... more

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Product information "Anti-RBL1"

Protein function: Key regulator of entry into cell division (PubMed:17671431). Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation (PubMed:8319904). May act as a tumor suppressor (PubMed:8319904). [The UniProt Consortium]

Keywords:	Anti-RBL1, Anti-pRb1, Anti-p107, Anti-Retinoblastoma-like protein 1, Anti-107 kDa retinoblastoma-associated protein, RBL1 Rabbit pAb
Supplier:	Assay Genie
Supplier-Nr:	CAB20518

Properties

Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RBL1 (NP_002886.2).