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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-AB-F1227US.25 | 25 µg | - |
7 - 16 business days* |
95.00€
|
|||
E-AB-F1227US.100 | 100 µg | - |
7 - 16 business days* |
257.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein... more
Product information "Anti-Rat CD45, Elab Fluor(R) Red 780 conjugated, clone OX-1"
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets, isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro. Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. [The UniProt Consortium]
Keywords: | Anti-CD45, Anti-T200, Anti-L-CA, Anti-Ptprc, EC=3.1.3.48, Anti-Leukocyte common antigen, Anti-Receptor-type tyrosine-protein phosphatase C, Elab Fluor(R) Red 780 Anti-Rat CD45 Antibody[OX-1] |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-F1227US |
Properties
Application: | FC, FC (membrane) |
Antibody Type: | Monoclonal |
Clone: | OX-1 |
Conjugate: | EF780 |
Host: | Mouse |
Species reactivity: | rat |
Database Information
KEGG ID : | K06478 | Matching products |
UniProt ID : | P04157 | Matching products |
Gene ID | GeneID 24699 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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