Anti-RANBP3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA043375.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA043375.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export... more

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Product information "Anti-RANBP3"

Protein function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 79% and to rat: 80%

Keywords:	Anti-RANBP3, Anti-RanBP3, Anti-Ran-binding protein 3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA043375

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LENSTNSADA SSNKFVFGQN MSERVLSPPK LNEVSSDANR ENAAAESGSE SSSQEATPEK ESLAESAAAY TKATARKCLL EKVEVITGE (ATA-APrEST82445)