Anti-RANBP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA023960.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA023960.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I... more

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Product information "Anti-RANBP2"

Protein function: E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I (PubMed:11792325, PubMed:12032081, PubMed:15378033, PubMed:22194619, PubMed:15931224). Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates (PubMed:7775481). Binds single-stranded RNA (in vitro) (PubMed:7775481). May bind DNA (PubMed:7775481). Component of the nuclear export pathway (PubMed:10078529). Specific docking site for the nuclear export factor exportin-1 (PubMed:10078529). Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB (PubMed:22155184). Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell cycle (PubMed:20386726). Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity (PubMed:20676357, PubMed:23353830). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 71% and to rat: 72%

Keywords:	Anti-p270, Anti-RANBP2, Anti-RanBP2, Anti-NUP358, Anti-Nucleoporin Nup358, Anti-358 kDa nucleoporin, Anti-Ran-binding protein 2, Anti-E3 SUMO-protein ligase RanBP2, Anti-Nuclear pore complex protein Nup358
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA023960

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: CGVCSDTDED NGNGEDFQSE LQKVQEAQKS QTEEITSTTD SVYTGGTEVM VPSFCKSEEP DSITKSISSP SVSSETMDKP VDLSTRKEID TDSTSQGESK IVSFGFGSST GLSFADLASS NS (ATA-APrEST73972)