Anti-Ran (Androgen Receptor-associated Protein 24, ARA24, Gsp1, GTP Binding Nuclear Protein RAN, GTP

Anti-Ran (Androgen Receptor-associated Protein 24, ARA24, Gsp1, GTP Binding Nuclear Protein RAN, GTP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
R1069-02.100 100 µl - -

3 - 19 business days

505.00€
 
Ran is a small GTPase of the Ras family that plays a central role in the spacial and temperal... more
Product information "Anti-Ran (Androgen Receptor-associated Protein 24, ARA24, Gsp1, GTP Binding Nuclear Protein RAN, GTP"
Ran is a small GTPase of the Ras family that plays a central role in the spacial and temperal organization of eukaryotic cells. During interphase, Ran-GDP localizes to the cytoplasm and Ran-GTP to the nucleus. This polarized localization of Ran ensures its role in nuclear transport. During mitosis, Ran-GTP is chromatin associated, where it promotes spindle assembly and nuclear envolope formation. In S phase, Ran-GTP associates with and inhibits MCM helicase, ensuring precise chromosomal DNA duplication during the cell cycle. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000. Incubate membrane with 1X TBS, 5% BSA. 0.1% Tween-20 at 4ºC with gentle shaking overnight., Optimal dilution determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: R1069-02

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Bovine, Hamster, Human, Monkey, Mouse, Rat
Immunogen: Polyclonal antibodies are produced by immunizing rabbits with two synthetic peptides (KLH-coupled) corresponding to amino acids surrounding Arg29 and Asn143 of human Ran.
Purity: Purified by Protein A affinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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