Anti-RAD54L

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA028954.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Plays an essential role in homologous recombination (HR) which is a major... more

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Product information "Anti-RAD54L"

Protein function: Plays an essential role in homologous recombination (HR) which is a major pathway for repairing DNA double-strand breaks (DSBs), single-stranded DNA (ssDNA) gaps, and stalled or collapsed replication forks (PubMed:9774452, PubMed:24798879, PubMed:32457312, PubMed:11459989, PubMed:12205100, PubMed:27264870). Acts as a molecular motor during the homology search and guides RAD51 ssDNA along a donor dsDNA thereby changing the homology search from the diffusion-based mechanism to a motor-guided mechanism. Plays also an essential role in RAD51-mediated synaptic complex formation which consists of three strands encased in a protein filament formed once homology is recognized. Once DNA strand exchange occured, dissociates RAD51 from nucleoprotein filaments formed on dsDNA. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 95%

Keywords:	Anti-hHR54, Anti-RAD54A, Anti-RAD54L, Anti-hRAD54, Anti-RAD54 homolog, Anti-DNA repair and recombination protein RAD54-like
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA028954

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TLMWTLLRQS PECKPEIDKA VVVSPSSLVK NWYNEVGKWL GGRIQPLAID GGSKDEIDQK LEGFMNQRGA RVSSPILIIS YETFRLHVGV LQKGSVGLVI CDEGHRLKNS ENQTYQALDS LNTSRRVLIS GTPIQNDLLE YFSLV (ATA-APrEST71056)