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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
040797-Biotin.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA... more
Product information "Anti-Rad50, CT (Rad50, DNA repair protein RAD50) (Azide Free) (Biotin)"
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation (By similarity). Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-Rad50, Anti-mRad50, EC=3.6.-.-, Anti-DNA repair protein RAD50 |
Supplier: | United States Biological |
Supplier-Nr: | 040797-Biotin |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | Biotin |
Host: | Rabbit |
Species reactivity: | mouse |
Immunogen: | Mouse Rad50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 910-938 amino acids from the C-terminal region of mouse Rad50. |
Format: | Affinity Purified |
Database Information
UniProt ID : | P70388 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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